The Hidden Dangers of Benzodiazepines: Are We Trading Anxiety for Addiction?
Benzodiazepines are a class of psychoactive drugs widely used in the treatment of anxiety, insomnia, seizures, and muscle spasms. They are among the most commonly prescribed medications worldwide due to their effectiveness and rapid onset of action (Griffin et al., 2013). However, their potential for dependence, misuse, and withdrawal symptoms make them a double-edged sword in medical practice (Lader, 2011). This article provides a detailed exploration of benzodiazepines, including their pharmacology, therapeutic applications, risks, and practical guidelines for safe use. It also addresses the dangers of misuse and strategies to minimize the risk of addiction and withdrawal complications. Pharmacology of Benzodiazepines Benzodiazepines act on the central nervous system (CNS) by enhancing the effect of gamma-aminobutyric acid (GABA), the brain’s primary inhibitory neurotransmitter. By binding to GABA-A receptors, these drugs increase GABAergic activity, leading to sedative,...